Motor impulsivity in Parkinson disease: Associations with COMT and DRD2 polymorphisms
نویسندگان
چکیده
منابع مشابه
Association of COMT and COMT-DRD2 interaction with creative potential
Several lines of evidence suggest that genes involved in dopamine (DA) transmission may contribute to creativity. Among these genes, the catechol-O-methyltransferase gene (COMT) and the dopamine D2 receptor gene (DRD2) are the most promising candidates. Our previous study has revealed evidence for the involvement of DRD2 in creative potential. The present study extended our previous study by sy...
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Performing sequences of movements is a ubiquitous skill that involves dopamine transmission. However, it is unclear which components of the dopamine system contribute to which aspects of motor sequence learning. Here we used a genetic approach to investigate the relationship between different components of the dopamine system and specific aspects of sequence learning in humans. In particular, w...
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Schizophrenia is a serious mental disorder that affects social function of patients. Clinical characteristics of schizophrenia are early onset age and prolonged disease course. With the extensive application of antipsychotics, there are significant improvements in the remission rate of psychotic symptoms such as impaired social function in schizophrenic patients. However, in recent years, disru...
متن کاملAggression and polymorphisms in AR, DAT1, DRD2, and COMT genes in Datoga pastoralists of Tanzania
The aim of this study was to analyse the relationships between polymorphisms in four candidate genes (AR, DAT1, DRD2, and COMT) and aggression in men from a traditional society of East African pastoralists, the Datoga. Buss and Perry's Aggression Questionnaire was used to measure aggression. The number of CAG repeats in the AR gene was negatively correlated with physical aggression, anger, and ...
متن کاملImpact of DRD2/ANKK1 and COMT Polymorphisms on Attention and Cognitive Functions in Schizophrenia
BACKGROUND Cognitive deficits such as poor selective attention and executive functions decline have been reported in patients with schizophrenia. Many studies have emphasized the role of dopamine in regulating cognitive functions in the general population as well as in schizophrenia. However, the relationship between cognitive processes, schizophrenia and dopaminergic candidate genes is an orig...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Psychology
سال: 2014
ISSN: 0036-5564
DOI: 10.1111/sjop.12113